ElevATP®
Common Name
ElevATP®
Top Benefits of ElevATP®
Supports athletic performance and body composition*
Supports power output and training volume*
Helps reduce performance decrements associated with overreaching*
Supports lean muscle and strength*
Supports healthy aging*
Supports ATP production*
Supports mitochondrial structure and function*
Supports cellular responses and antioxidant defenses*
Supports healthy gut microbiota*
What is ElevATP®?
ElevATP® is a proprietary, clinically researched combination of a water extract of “ancient peat” (fossilized plants) and apple extract. The ancient peat contains 70 plant-derived inorganic microelements. It is especially rich in carbon, magnesium, nitrogen, oxygen, and sulfur. The apple extract is made from apple peel and contains 10 apple polyphenols. ElevATP® was designed to support mitochondrial energy-producing processes to stimulate cellular energy production in the form of ATP. Having extra ATP allows our cells to do more things better, upregulating health, performance, and metabolism.*
Qualia ElevATP® Sourcing
elevATP® is a clinically tested product with human studies for sports performance, body composition, and elevating cellular energy in the form of ATP.
Created by FutureCeuticals, Inc., an industry leader in the research, development and manufacture of fruit, vegetable, and grain-based products.
elevATP® was awarded ingredient of the year in the sports nutrition category by Nutraingredients-USA Awards for 2018.
elevATP® is Non-GMO Project Verified, vegan, GRAS (generally recognized as safe) and gluten free.
elevATP® is a registered trademark of VDF FutureCeuticals, Inc. elevATP® products are protected by US patent no. 9,327,005, used under license.
ElevATP® Dosing Principles and Rationale
The dose of elevATP® used in human clinical research has been 150 mg once daily. We opted to use this dose in our formulation. In general, we consider polyphenols, like those found in the apple peel extract component of elevATP® to be subject to hormetic dosing principles (see Neurohacker Dosing Principles). Flavonoids are additive, and often complementary with other polyphenol compounds, so the combination of all polyphenols in a formulation should be considered when determining dosage (not the amount of a single polyphenol molecule in isolation).*
ElevATP® Key Mechanisms
Supports mitochondrial function and structure*
Stimulates ATP production [1–5]
Protects from mitochondrial dysfunction [1]
Promotes mitochondrial dehydrogenase activity [6]
Protects from complex I (NADH-coenzyme Q reductase) inhibition [4]
Supports mitochondrial β-oxidation performance [5]
Upregulates peroxisome proliferator-activated receptor alpha (PPARα) [7]
Supports healthy mitochondrial membrane potential [1]
Supports healthy mitochondrial DNA (mtDNA) [6]
Supports healthy mitochondrial morphology [5]
Supports peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1α) (mitochondrial biogenesis) [5,6,8]
Promotes exercise performance*
Supports endurance performance [9,10]
Supports strength performance [11]
Supports muscle structure and function [7,9]
Supports lean mass [12,13]
Supports a healthy skeletal system*
Supports cartilage structure [6]
Supports antioxidant defenses*
Supports antioxidant defenses [6,8]
Counters oxidative stress [1,4,5,8]
Replenishes glutathione (GSH) levels [1]
Supports healthy mitochondrial redox status [1,4,5]
Supports a healthy gut microbiota*
Supports a healthy composition of the gut microbiota [14,15]
Supports gut microbial metabolism [14,16]
Promotes healthy aging and longevity*
Supports SIRT-1 [17]
Influences mTOR signaling [3]
Supports healthy immune signaling [5,8]
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.
REFERENCES
[1]C. Carrasco-Pozo, M. Gotteland, H. Speisky, J. Pharm. Pharmacol. 62 (2010) 943–950.
[2]T. Reyes-Izquierdo, C. Shu, R. Argumedo, B. Nemzer, Z. Pietrzkowski, J Aging Res Clin Practice 3 (2014) 56–60.
[3]T. Reyes-Izquierdo, B. Nemzer, R. Argumedo, C. Shu, L. Huynh, Z. Pietrzkowski, J Aging Res Clin Practice 2 (2013) 178–184.
[4]C. Carrasco-Pozo, M. Gotteland, H. Speisky, J. Agric. Food Chem. 59 (2011) 11501–11508.
[5]P.R. Yeganeh, J. Leahy, S. Spahis, N. Patey, Y. Desjardins, D. Roy, E. Delvin, C. Garofalo, J.-P. Leduc-Gaudet, D. St-Pierre, J.-F. Beaulieu, A. Marette, G. Gouspillou, E. Levy, J. Nutr. Biochem. 57 (2018) 56–66.
[6]I. Masuda, M. Koike, S. Nakashima, Y. Mizutani, Y. Ozawa, K. Watanabe, Y. Sawada, H. Sugiyama, A. Sugimoto, H. Nojiri, K. Sashihara, K. Yokote, T. Shimizu, Sci. Rep. 8 (2018) 7229.
[7]K. Nakazato, H. Song, T. Waga, Med. Sci. Sports Exerc. 39 (2007) 934–940.
[8]M.C. Denis, A. Furtos, S. Dudonné, A. Montoudis, C. Garofalo, Y. Desjardins, E. Delvin, E. Levy, PLoS One 8 (2013) e53725.
[9]W. Mizunoya, H. Miyahara, S. Okamoto, M. Akahoshi, T. Suzuki, M.-K.Q. Do, H. Ohtsubo, Y. Komiya, M. Lan, T. Waga, A. Iwata, K. Nakazato, Y. Ikeuchi, J.E. Anderson, R. Tatsumi, PLoS One 10 (2015) e0134303.
[10]T. Reyes-Izquierdo, B. Nemzer, R. Argumedo, M. Cervantes, Z. Pietrzkowski, Journal of Nutraceuticals and Food Science 1 (2016) 11.
[11]J.M. Joy, R.M. Vogel, J.R. Moon, P.H. Falcone, M.M. Mosman, Z. Pietrzkowski, T. Reyes, M.P. Kim, BMC Complement. Altern. Med. 16 (2016) 224.
[12]J.M. Joy, P.H. Falcone, R.M. Vogel, M.M. Mosman, M.P. Kim, J.R. Moon, Appl. Physiol. Nutr. Metab. 40 (2015) 1171–1177.
[13]J.M. Joy, R.M. Vogel, J.R. Moon, P.H. Falcone, M.M. Mosman, M.P. Kim, J. Int. Soc. Sports Nutr. 13 (2016) 25.
[14]A. Koutsos, M. Lima, L. Conterno, M. Gasperotti, M. Bianchi, F. Fava, U. Vrhovsek, J.A. Lovegrove, K.M. Tuohy, Nutrients 9 (2017).
[15]A. Cuervo, A. Hevia, P. López, A. Suárez, B. Sánchez, A. Margolles, S. González, Nutrients 7 (2015) 1301–1317.
[16]G. Ravn-Haren, B.N. Krath, J. Markowski, M. Poulsen, M. Hansen, K. Kołodziejczyk, M. Kosmala, L.O. Dragsted, Food Funct. 9 (2018) 2931–2941.
[17]T. Sunagawa, T. Shimizu, T. Kanda, M. Tagashira, M. Sami, T. Shirasawa, Planta Med. 77 (2011) 122–127.