Rosemary (Rosmarinus officinalis) Leaf Extract

COMMON NAME 

Rosemary | Garden Rosemary

TOP BENEFITS OF ROSEMARY LEAF EXTRACT

Supports healthy aging*

Supports skin health*

Supports antioxidant defenses*

Supports healthy gut microbiota* 

WHAT IS ROSEMARY LEAF EXTRACT?

Rosemary is a member of the mint family. Its common name derives from Latin and translates as “dew of the sea.” Rosemary was used as a spice and herb by Egyptians, Greeks, and Latins cultures, thriving close to the coast, especially in dryer areas throughout the Mediterranean. Rosmarinus officinalis contains a range of health-supporting polyphenols, including diterpenes (e.g., carnosol, carnosic acid, rosmarinic acid), triterpenes (e.g., ursolic acid), and flavonoids (e.g., luteolin).* The diterpenes carnosol and carnosic acid are potent antioxidants that account for over 90% of the antioxidant activity in rosemary leaves [1].* 

Qualia ROSEMARY LEAF EXTRACT SOURCING

Rosemary Leaf Extract is standardized to contain 7.5% Carnosic Acid + Carnosol.

Rosemary Leaf Extract is gluten-free, non-GMO, vegan, Kosher, and Halal certified.

ROSEMARY LEAF EXTRACT DOSING PRINCIPLES AND RATIONALE

We believe that rosemary extracts standardized for diterpenes should be thought of as following a threshold response (see Neurohacker Dosing Principles). This means that beyond a certain dose, there may be no additional functional benefits gained. As an example, a skin health study supplemented either 50 mg or 125 mg of a rosemary extract combined with similar amounts of a citrus extract. The lower dose performed as well as the higher dose [2]. In several skin studies where rosemary has been combined with lycopene-rich tomato fruit extracts, the dose used was also an amount closer to this 50 mg range of a standardized extract. Our dose for this rosemary extract was selected to be consistent with an amount that has been used when rosemary extracts have been combined with other skin health ingredients.*

ROSEMARY LEAF EXTRACT KEY MECHANISMS

Supports skin health*

Influences ECM breakdown enzymes [3]

Supports free radical scavenging [4]

Helps quench free radicals [3,5]

Supports skin antioxidant defenses [6]

Supports Nrf2 signaling [7,8]

Counters ROS-induced premature senescence [7]

Supports skin DNA integrity and repair [3,5,9]

Supports immune signaling [10–13]

Supports skin in adapting to environmental stress [9]

Influences AhR signaling [14]

Supports antioxidant defenses*

Supports antioxidant defenses [15–21]

Counters reactive oxygen species (ROS) production [16]

Supports Nrf2 signaling [7,22,23]

Supports phase II detoxification enzymes [24,25]

Supports brain function*

Supports neuroprotective functions [19,23]

Supports brain antioxidant defenses [23]

Counters ROS production and oxidative stress in the brain [16,19,23]

Supports a healthy gut microbiota*

Supports healthy gut microbiota [26]

Supports healthy gut microbial metabolism [26]

Supports healthy aging and longevity*

Supports maintenance of healthy cholesterol levels [18]

Supports maintenance of healthy insulin sensitivity [21]

Supports healthy body weight [21]

Supports maintenance of healthy blood/liver lipid levels [21,27]

Supports AMP-activated protein kinase (AMPK) signaling [27–29]

Supports SIRT1 and SIRT6 signaling [30] 

Counters advanced glycation end-products (AGEs) production [21,31]

Influences immune signaling [18,21] 

Complementary ingredients*

Lycopene to support skin health [32,33]

Citrus extracts to support skin health [2,34]

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, cure, or prevent any disease.

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