TRANS-RESVERATROL (trans-3, 5, 4'-trihydroxystilbene) in Qualia NAD+ is usually just called resveratrol. It is a stilbenoid, a type of natural polyphenol found in plants. Resveratrol has been the subject of thousands of pre-clinical and clinical research studies. It is best known for supporting healthy aging functions, and for supporting metabolism, heart health, immune health, and cognition.* Resveratrol is a defense compound that plants make more of when exposed to environmental stressors. It toughens them up, making them more resistant to stress.
MAGNESIUM (from Aquamin® MG)in Qualia NAD+. Magnesium is one of the most abundant minerals in the body and plays a vital role in supporting the function of all living cells. It’s used in more than 300 enzymes. ATP (i.e., cellular energy) occurs complexed with magnesium, so all enzymes utilizing ATP require magnesium to support their activity. ATP production, particularly through mitochondrial processes, promotes greater NAD+ turnover (the continuous use and recycling of NAD+).*
COFFEEBERRY® in Qualia NAD+ is made from organic coffee fruits, which are often called coffee cherries. Like cherries, coffee plants produce soft red fruits surrounding a pit or hard seed. The seed (or coffee "bean") is roasted to make coffee. But it’s the fruit that is being used to make Coffeeberry®. Similar to many fruits, coffee cherries are high in polyphenols. And like coffee beans, they also contain caffeine. Caffeine has been found to activate AMPK, a key energy-sensing enzyme that plays a significant role in promoting NAD+ biosynthesis.*
B-COMPLEX VITAMINS (from Saccharomyces cerevisiae culture) in Qualia NAD+ is an inactivated yeast that provides all eight B vitamins (and thus 8 ingredients within the Qualia NAD+ formula): thiamine (B1), riboflavin (B2), niacin (B3), pantothenic acid (B5), pyridoxine (B6), biotin (B7), folic acid (B9), and cobalamin (B12). B vitamins have essential roles in cellular metabolism and energy production. Every B vitamin is either a cofactor or a precursor of a cofactor for a key metabolic process. B vitamins are essential for the generation of cell energy as ATP in mitochondria.*
LUTEOLIN found in Qualia Senolytic, is a yellow plant pigment used for centuries as a yellow dye. In fact, the latin name for yellow is luteus. Luteolin has a very similar molecular structure to quercetin, and much like fisetin, luteolin has also shown evidence of senolytic properties by helping the body manage senescent cell elimination.*
LONGVIDA OPTIMIZED CURCUMIN® EXTRACTis found in Qualia Senolytic. Curcumin is the pigment in turmeric that results in its yellow-orange coloring. Curcumin appears to provide senolytic support in intervertebral disc cells, but much like quercetin, it has poor bioavailability. Longvida Optimized Curcumin® Extract was developed to overcome this bioavailability hurdle and has been researched in human studies in areas including cognitive function, mood, exercise recovery, and joint health.*
SENACTIV® is a patented blend of notoginseng root and chestnut rose hips. It has been shown to support exercise recovery and management of senescent cells in muscle. This provides an asset within our formula to help counteract the slow workout recoveries that are common with the human aging process.You can find it in Qualia Senolytic.
OLIVE LEAF EXTRACT Oleuropein (a secoiridoid polyphenol) is found in high amounts within olive leaves. Our particular olive leaf extract is standardized for 40% oleuropein. A 2020 study showed that oleuropein supports the management of senescent chondrocytes—chondrocytes are the cells that create cartilage and support healthy joints (an area of our bodies which commonly experience noticeable negative aging symptoms).* Olive leaf extract is a key ingredient in Qualia Senolytic.
MILK THISTLE FRUIT EXTRACT (found in Qualia Senolytic). The seed-like fruits from milk thistle (Silybum marianum) have been in Mediterranean diets for over 2,000 years. The main active substance in milk thistle is silymarin. Our extract is standardized to 80% silymarin by spectrophotometry, and has potential in playing a complementary role to other ingredients in Qualia Senolytic, particularly the stressed cell support of curcumin.*
SOYBEAN SEED EXTRACT Soybean seeds, like most legumes, contain a type of bioflavonoid called isoflavonoids. Our soybean seed extract is standardized at 40% isoflavones which shows promise as having a complementary role in our overall formulation. Daidzein, for example (an isoflavonoid in our extract) is one of the top four compounds identified as a possible candidate for helping manage some types of senescent cells.* You can find it in Qualia Senolytic.
OKINAWA MOZUKU EXTRACT is a brown seaweed grown in the coastal waters of Okinawa, where it is a foundational superfood in this blue zone’s diet. This extract contains ≥85% fucoidan, which provides support for a healthy immune system and for stem cell functions including stem cell mobilization and migration.* You can find it in Qualia Stem Cell.
ASTRAGALUS ROOT EXTRACT found in Qualia Stem Cell. Astragalus membranaceus, or Huang Qi, is a perennial herb native to northeast Asia, flourishing in dry, sandy soils and regions such as mountain thickets and vast grasslands. In Traditional Chinese Medicine it is one of the most important herbs for tonifying Qi and enhancing vitality, and is also renowned for healing and promoting healthy blood circulation. Preclinical studies suggest that Astragalus root aids healing by promoting healthy stem cell proliferation and differentiation.*
SALVIA MILTIORRHIZA EXTRACT found in Qualia Stem Cell. Salvia miltiorrhiza, known as Danshen in Traditional Chinese Medicine, primarily grows in the rich, earthy soils of East Asia’s temperate and subtropical regions along hillsides, moist stream banks, and in cool, shaded forests. Traditionally, Danshen was believed to have an affinity for the heart and was used to promote heart health, blood circulation, and healing. Preclinically, Danshen has been shown to support the healthy differentiation and proliferation of various stem cell types, leading to improved tissue health like heart and liver.*
WHITE PEONY ROOT EXTRACT in Qualia Stem Cell, is a Traditional Chinese Medicine native to central and eastern Asia that grows in a variety of environments, such as glasslands, woodland edges, dry meadows and sunny slopes. Paeoniflorin, a primary bioactive compound extracted from the roots of white peony, is known to maintain a balanced activity of CDC42, which is a crucial mechanism for stem cell rejuvenation. Preclinical studies show that paeoniflorin supports healthy stem cell proliferation, differentiation, and self-renewal, driving tissue regeneration.
SODIUM COPPER CHLOROPHYLLIN in Qualia Stem Cell is derived from chlorophyll, the vibrant green pigment found in plants and algae that plays a crucial role in photosynthesis. In preclinical studies, this compound helps protect stem cells against oxidative stress and supports healthy stem cell proliferation and differentiation.*
L-SERINE in Qualia Stem Cell is an amino acid essential for protein synthesis and plays a vital role in stem cell function and maintenance. It is also required for nucleotide synthesis - the basic building blocks of DNA and RNA - which supports stem cell division, proliferation, and growth.*
NUCLEOPRIME® NUCLEOTIDES BLEND Nucleotides are the complex molecules that form DNA and RNA. DNA is sometimes referred to as the "blueprint for life", and RNA translates the information stored in DNA to make the proteins and express our genes. They are essential compounds during times of tissue self-renewal so act a bit like fuel for numerous stem cell functions.* Found in Qualia Stem Cell.
WELLMUNE® SOLUBLE YEAST BETA GLUCAN Wellmune® Soluble supports the body’s natural defenses. Over a dozen clinical trials demonstrate the ability of Wellmune® to help maintain a healthy immune system and support overall energy and vitality. The soluble beta-glucans in Wellmune support healthy stem cell migration, renewal, and survival mechanisms.* Found in Qualia Stem Cell.
BROMELAIN in Qualia Stem Cell is a mixture of protein digesting enzymes derived primarily from the stem and fruit of the pineapple known for its use in promoting a healthy inflammatory response, in supporting tissue healing, and in supporting the production of extracellular matrix components, such as collagen. Preclinical studies demonstrate their ability to support creation of a favorable microenvironment for stem cell activities and tissue regeneration.*
PANAX NOTOGINSING ROOT EXTRACT Panax notoginseng, or Sanqi/Tianqi in Traditional Chinese Medicine, is a prized medicinal plant native to the warm mountainous regions of Southwest China, and is known for promoting healthy blood circulation, supporting healing, and supporting the immune system. In preclinical studies, Panax notoginseng root has been shown to support the healthy differentiation and proliferation of various stem cell types, leading to improved tissue renewal.* Found in Qualia Stem Cell.
FERULIC ACID, the primary bioactive compound in Angelica sinensis (Danggui in Traditional Chinese Medicine), is mainly responsible for its antioxidant properties and ability to support healing through the formation of healthy new blood vessels. Besides the preclinical evidence that it supports healthy stem cell differentiation, it is also known to support stem cell self-renewal, or maintenance of the stem cell pool over time.* Found in Qualia Stem Cell.
ROYAL JELLY POWDER Royal jelly is the nutrient-rich secretion produced by worker honeybees exclusively for the queen bee and young, known especially for supporting the queen’s longevity, fertility, and vitality. It contains a complex of bioactive compounds, including the unique fatty acid 10-hydroxy-2-decenoic acid (10-HDA), which preclinical studies have shown promotes stem cell proliferation and differentiation, promotes telomere health and supports cellular health.* Found in Qualia Stem Cell.