What follows is a transcript from a discussion with Dr. Jon Lieff, where we explore the captivating journey into the inner workings of cells and reveals their hidden language.
What follows is a transcript from a discussion with Dr. Jon Lieff, where we explore the captivating journey into the inner workings of cells and reveals their hidden language.
In this article, we’re going to introduce an indirect way of supporting NAD+. Rather than making more, this article will be teaching you about using less. Using less requires downregulating a protein called cluster of differentiation 38 (CD38 for short). When CD38 is not as active, less NAD+ is used by it. The result is higher NAD+ levels and greater NAD+ availability for important healthy aging uses.
The NAD+ form of the molecule is required for certain cellular signaling reactions that change the way cells behave. Unlike redox, where the molecule is conserved, the NAD+ molecule is broken apart or “consumed” when used for signaling. It’s these NAD+ consumption uses that have been a main reason for the resurgence of scientific interest in strategies to boost NAD+.