What is Qualia Senolytic? It is a dietary supplement formulated to help bring the creation and removal of senescent cells back into a healthy balance. Here's a deep dive into the ingredients included in the formulation.
Articles in Healthspan
Selectively eliminating dysfunctional mitochondria (mitophagy) and replacing them with new mitochondria (mitochondrial biogenesis) helps us stay biologically younger. But what exactly are the functions of mitochondria and how does mitochondrial health affect aging?
Is science on the cusp of changing the future of disease prevention via a deeper understanding of an individual’s biology at a molecular level?
In Silicon Valley, the hub of anti-aging research and funding, countless entrepreneurs and high-profile celebrities use fasting to combat the effects of aging. In Anti-Aging Benefits of Fasting, we will explore the mechanisms that create these fasting benefits. This part is more scientific than the others, but we emphasize only crucial components in an easily digestible format.
A recent article in the New York Post suggested that wearing glasses might offer some degree of protection against respiratory viruses. We’ve also read in quite a few places comments about wearing eye protection as a possible respiratory virus prevention suggestion. Is it likely to work?
In this article we’ll be covering the “big picture” when it comes to NAD. We’ll be doing a deeper dive on specific topics we introduce in this article in subsequent articles in this series. As you go through this series of articles please keep in mind that, like other molecules in the body, NAD+ is a means to an end. We don’t care about NAD+ on its own; we care about it because of what it allows cells to do.
In 1958, Jack Preiss and Philip Handler published a scientific paper describing how NAD+ was made from niacin in three steps.(1) This pathway was later named the Preiss-Handler pathway after the co-discoverers. It describes the enzyme steps needed to convert niacin into the NAD+ molecule.
The NAD+ form of the molecule is required for certain cellular signaling reactions that change the way cells behave. Unlike redox, where the molecule is conserved, the NAD+ molecule is broken apart or “consumed” when used for signaling. It’s these NAD+ consumption uses that have been a main reason for the resurgence of scientific interest in strategies to boost NAD+.
Our bodies and brain thrive on short-term acute “stress” exposure by ramping up growth and repair. Here are three science-backed ways to increase resilience with hormesis.
The gut microbiota influences many aspects of human physiology, from metabolism, to the cardiovascular system or the nervous system, for example. In this article, we focus on the interaction between the gut microbiota and our immune system.
The salvage pathway is used to produce NAD+ from nicotinamide molecules. Whether the source of the nicotinamide is vitamin B3 (as niacinamide), newer nicotinamides (e.g., nicotinamide riboside [NR], nicotinamide mononucleotide [NMN]), or molecules in food that get broken down during digestion into nicotinamide, the salvage pathway turns them into NAD+ in our tissues.
Any way we can boost mitochondria helps us to increase the longevity of our cells and support energy production. In this article, we explore lifestyle habits that improve mitochondrial health and support healthy aging.
Viruses are everywhere cellular life is present, often in unfathomable numbers. They mutate very often, frequently by recombining with other viruses. This means that new viruses are constantly being generated.
As we’ll learn in this article, viruses are very simple, but despite their simplicity, they are very effective and impressive little creatures. We’ll also learn how our immune system rises to the challenge.
The adaptive immune system is responsible for the more complex and optimized immune responses that develop when innate immunity is insufficient to manage a threat. It is the specific immunity we acquire over time as the immune system is challenged with new antigens and learns to deal with them.
The citric acid cycle, also known as the Krebs cycle or tricarboxylic acid (TCA) cycle, is a circular loop rotating through eight organic acid intermediates (e.g., citrate, malate, oxaloacetate). This cycle plays a critical role in moving cell energy production forward, because it is the first pathway of the final stage of energy extraction from nutrients, in which carbon units are fully oxidized. The intermediate products formed in this cycle are also used to build molecules including proteins, DNA, and RNA.
To improve our healthcare we need important research that is not being done. Often times health topics aren't studied due to lack of funds and resources. We’ve been asking our podcast guests where the missing research is in the field they are experts in. Read on to find out what they said.
Fatty acids are an important fuel for the generation of cell energy in the form of adenosine triphosphate (ATP). Fatty acid oxidation, also known as beta-oxidation, is the metabolic pathway of fatty acid breakdown for energy production. Fatty acids are the primary source of energy for the heart (i.e., the cardiac muscle) and skeletal muscle during rest or moderate physical activity.
The immune system is the collection of cells, tissues, and molecules that work together to recognize the healthy cells that make up the body, and protect us against the unfamiliar or damaged.
The immune system monitors our body continuously searching for certain categories of things that may threaten our health: infectious microbes, viruses, fungi, and parasites (i.e., germs or pathogens); toxic cellular products; and damaged or diseased cells, including senescent or tumor cells.
One of the public health goals of prevention is “flattening the epidemic curve*,” which essentially means decreasing the growth of new infections now, so they can be spread out over time. This is the reason why businesses are asking employees to work from home and governments are enacting policies to support social distancing strategies. In essence, public health wants to push some of the infections that might otherwise occur in the next weeks to sometime in the future … the further into the future the better.
There’s no data suggesting that gargling prevents infection from the virus causing COVID-19. The SARS-CoV-2 virus is too new to know. But, in general, gargling might have modest preventive benefit for colds (and likely less so for the flu). Once someone has an upper respiratory infection, gargling is not a treatment for the infection. It would, at best, offer some degree of soothing of sore throat symptoms.
Similar to many other cellular processes, the creation of new mitochondria (a process called mitochondrial biogenesis), and the interacting pathways that influence it, suffers with aging. This is the bad news. The good news is that there are things we can do to better support maintaining a fitter mitochondrial network.
During the development of Qualia Senolytic, Neurohacker Collective put our newest healthy aging product to the test to find out how users would respond.
Any way we can boost mitochondria helps us to increase the longevity of our cells and support energy production. Here we explore temperature and light therapy to improve mitochondrial health and support healthy aging.
Matt Maruca, CEO of Ra Optics, shares with us 8 steps to optimizing, both mitochondrial and vision health through the power of light
Immunometabolism is the crosstalk between metabolic and immunological processes. Mitochondria, the cellular structures that generate cell energy, are key elements in the crosstalk between metabolic and immune signaling pathways.
